This is based on a few things…mainly the fact that certain feminine hygiene products have a body and tail and are remarkably mouse-like. There was also a cat cartoon I saw years ago that was somewhat more graphic than my version (but then it involved Siamese, too); unfortunately I have no idea where I saw it and I can’t find it again or I would link to it. And then there was this incident…So yeah. It happens. Google it.
I really love how proud Jacoby is of himself in this cartoon. You know he was the instigator. Although I do apologise to anyone who doesn’t like cartoons resorting to bathroom humour.
(Click cartoon to embiggen, or you can view all cartoons in Slideshow mode on Flickr.)